SWISS PEPTIDE FORMULA

One Cream. Everything Your Skin Needs.

Swiss-developed formula engineered to replace your multi-step routine. Delivering hydration, barrier repair and clinical-grade anti-ageing in a single, precisely balanced application.

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4.8 / 5 · Verified Reviews

4.8/5 from our customers

Made in Switzerland

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Clinically Tested Ingredients

Your Old Routine

Old Routine

01

Cleanser

02

Exfoliant

03

Retinol serum

04

Barrier Repair Serum

05

Moisturising Cream

06

Face Oil

The Unique Base Routine

New Routine

✓

Cleanse

DISCOVER unique base

One Step. Superior Results.

4 clinically-studied peptides, working in harmony

10× Actives

Clinical-Grade Peptide Architecture

Formulated with Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7, this clinically driven complex supports collagen integrity, firmness, and the appearance of expression lines.

Ingredient study

Of Palmitoyl Tetrapeptide-7 and Palmitoyl Tripeptide-1
Independent Peer-Reviewed Peptide Results
+71% increase in firmness reported by participants at 8 weeks
N=32 Participants, 20-55 Age range, Randomized: Double blind trial

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DR. ELENA PRUSS, MD, PhD

25+ Years of Personalized Medicine.

At the centre I founded and run, we have for over two decades developed solutions in preventive care. Too often I see clients with damaged skin caused not by neglect, but by too many products interfering with each other. Unique Base was developed at the request of our clients as the clinical answer. Not a shortcut. A more intelligent approach.

20+ Years

Cellular aging research

Developed a Specialized Genetic Skin Test

Testing which ingredients harm the skin

RCLIN Board Member

Swiss Center for Genetics

“Unique Base cream is the result of years of our Team's dedication to finding the best possible solution, that would replace long and incompatible routines.”

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FLAGSHIP PRODUCT

Unique Base

Effective, yet gentle.

01

Peptide-Driven Firmness

Three signal peptides stimulate collagen synthesis. The results of retinol, without the irritation or downtime.

02

Barrier Repair Smoothing

Ceramide NP and hydrogenated lecithin restore the lipid barrier, without a need for an additional barrier repair ceam.

03

Antioxidant Enabled Calming

A soothing antioxidant and carrier peptide blend helps calm visible stress and reduce the appearance of fine lines, without the need for a separate serum.

04

Deep Hydration Plumping

Multi-level humectants complex penetrates all skin layers, not just the surface film that most moisturizers address.

$336.00 50ml

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50ml · Full Routine

A 30-day supply, Replaces 5 products.

Developed at The Swiss Centre for Genetics, Montreux

SOCIAL PROOF

Real women. Real results.

Verified Buyer

I have found Unique Base by @drpruss to be intensely hydrating. And it's given me such a radiance boost.

Isabelle Handley-Allen

Verified Buyer

I'm obsessed with this moisturiser. It's rich, thick, and intensely hydrating — but what truly sets it apart is its adaptive formula.

Rosalind Ann Weinberg

Verified Buyer

This formula penetrates the first layer of skin to then adjusts to the skin's current needs.

Veronica Genest

VISIBLE RESULTS

Measured Outcomes. Visible Change.

Each peptide ingredient has been independently studied:

70%

Copper Tripeptide-1

In a 12-week study of Copper Tripeptide-1, 70% of participants an increase in collagen production was observed in 70% of participants.

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97.3%

Hexapeptide-8

In a 12-week study of Hexapeptide-8, 97.3% of participants observed an improvement in the appearance of fine lines and wrinkles.

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81.25%

Palmitoyl Tripeptide-1

In a 14-day study of Palmitoyl Tripeptide-1, 81.25% of participants reported smoother looking skin.

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Texture & Experience

Feels LikeNothing. Does Everything.

Not a heavy cream. Not a thin serum. Unique Base is a skin-identical emulsion weightless on application, absorbed within seconds, leaving no film or residue. Designed to disappear into skin, while delivering at clinical depth.

7s

Average absorption time

0

Fragrance & parabens

pH 5.5

Skin-matched formulation

VIEW Science List

PRECISION EXTENSION

DR PRUSS · Magic Lift

Magic Lift, Eye Cream

Formulated specifically for the delicate periorbital area, Magic Lift extends the delivery system by leveraging peptides and natural film-forming actives to address fine lines, wrinkles, and the loss of firmness where it manifests earliest. Designed to work in conjunction with Unique Base not independently of it.

$259.00 15ml

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