SWISS PEPTIDE FORMULA

One Cream. Everything Your Skin Needs.

Swiss-developed formula engineered to replace your multi-step routine. Delivering hydration, barrier repair and clinical-grade anti-ageing in a single, precisely balanced application.

4.8 / 5 · Verified Reviews

4.8/5 from our customers
Made in Switzerland
Free Shipping
Clinically Tested
From Complexity to Precision

Performance Without the Layers.

Layering multiple formulas overwhelms the skin and complicates results. Unique Base delivers coordinated hydration, barrier support, and peptide-driven performance in one balanced step.

Your Old Routine

Old Routine
01
Cleanser
02
Exfoliant
03
Retinol serum
04
Barrier Repair Serum
05
Moisturising Cream
06
Face Oil

The Unique Base Routine

New Routine
Routine image
Cleanse

One Step. Superior Results.

4 clinically-studied peptides, working in harmony

10× Actives
Clinical-Grade Peptide Architecture
Formulated with Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7, this clinically driven complex supports collagen integrity, firmness, and the appearance of expression lines.
Product study of Unique Base
  • Clinically tested
  • 81% of participants reported fewer visible imperfections after 28 days
  • Independent study under dermatological supervision
  • N=22 Participants, 37-65 Age range
DR. ELENA PRUSS, MD, PhD​

25+ Years of Personalised Medicine.

At the centre I founded and run, we have for over two decades developed solutions in preventive care. Too often I see clients with damaged skin caused not by neglect, but by too many products interfering with each other. Unique Base was developed at the request of our clients as the clinical answer. Not a shortcut. A more intelligent approach.

20+ Years

Cellular ageing research

Developed a Specialised Genetic Skin Test

Testing which ingredients harm the skin ​

RCLIN Board Member

Swiss Center for Genetics

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“Unique Base cream is the result of years of our Team's dedication to finding the best possible solution that would replace long and incompatible routines.”​
FLAGSHIP PRODUCT

Unique Base

Effective, yet gentle.
01
​Peptide-Driven Firmness
Three signal peptides stimulate collagen synthesis. The results of retinol, without the irritation or downtime.​
02
​Barrier Repair Smoothing
Ceramide NP and hydrogenated lecithin restore the lipid barrier, without a need for an additional barrier repair cream.
03
Antioxidant Enabled Calming
A soothing antioxidant and carrier peptide blend helps calm visible stress and reduce the appearance of fine lines, without the need for a separate serum.
04
Deep Hydration Plumping
Multi-level humectant complex penetrates all skin layers, not just the surface film that most moisturisers address.
CHF 260.00 50ml
50ml · Full Routine
A 60-day supply. Replaces 5 products.
Developed at The Swiss Center for Genetics, Montreux

SOCIAL PROOF

Real women. Real results.

Verified Buyer

I have found Unique Base by @drpruss to be intensely hydrating. And it's given me such a radiance boost.

Isabelle Handley-Allen
Verified Buyer

I'm obsessed with this moisturiser. It's rich, thick, and intensely hydrating — but what truly sets it apart is its adaptive formula.

Rosalind Ann Weinberg
Verified Buyer

This formula penetrates the first layer of skin to then adjusts to the skin's current needs.

Veronica Genest
VISIBLE RESULTS
Measured Outcomes. Visible Change.
Independent study under dermatological supervision
81%
report fewer visible imperfections
81% of participants reported fewer visible imperfections after 28 days of use.
90%
say it replaces several products
In a 4-week study of Unique Base Face cream, 90% of participants reported that the product replaced several products in their usual skincare routine.
95%
say skin looks noticeably brighter
95% of participants reported that after 28 days of using Unique Base, their skin looked noticeably brighter and more radiant.
Texture & Experience
Feels Like Nothing. Does Everything.
Not a heavy cream. Not a thin serum. Unique Base is a skin-identical emulsion that is weightless on application, absorbed within seconds, leaving no film or residue. Designed to disappear into skin, while delivering at clinical depth.
7s
Average absorption time
0
Fragrance & parabens
pH 5.5
Skin-matched formulation
Read the science
PRECISION EXTENSION
DR PRUSS · Magic Lift
Magic Lift, Eye Cream
Formulated specifically for the delicate periorbital area, Magic Lift extends the delivery system by leveraging peptides and natural film-forming actives to address fine lines, wrinkles, and the loss of firmness where it manifests earliest. Designed to work in conjunction with Unique Base, not independently of it.
CHF 200.00 15ml

Begin Your Routine

One Cream.

Everything Your Skin Needs.

Swiss-developed. Clinician-formulated. Designed to simplify and to outperform.

Swiss Made & Certified Swiss Made & Certified
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