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Formulated Where Science Meets Skin.

DR PRUSS was not created to add another step to your routine.
It was created to solve a clinical pattern repeatedly observed in practice: increasingly layered products, skin increasingly reactive, and lipid barrier increasingly overwhelmed.
Dr. Elena Pruss, MD, PhD

25+ Years of Personalised Medicine.

At the centre I founded and run, we have for over two decades developed solutions in preventive care and personalised medicine. Too often I see patients with damaged barriers and sensitised skin caused not by neglect, but by too many products interfering with each other. Unique Base was developed at the request of our clients as the clinical answer. Not a shortcut. A more intelligent approach.

20+ Years

Cellular ageing research​

Developed a Specialised Genetic Skin Test​

Testing which ingredients harm the skin ​

RCLIN Board Member​

Swiss Center for Genetics​

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“Unique Base cream is the result of years of our Team’s dedication to finding the best possible solution, that would replace long and incompatible routines.”​
Research and Development Centre
Where the research behind Unique Base was independently developed.
THE RESEARCH
From Clinical Observation to Coordinated Architecture.
Every formulation begins with a question.
01
The Observation
Repeated skin barrier disruption at the cellular level.

Women presenting skin with dehydration and loss of firmness and inflammation despite consistent skincare use. The common factor was not neglect. It was accumulation. Too many isolated and often incompatible actives. Too little actual skin support.

02
The Insight
Most formulas compete rather than cooperate.

Different pH levels. Different absorption rates. Uncoordinated ingredient delivery. Layering increased complexity, but not necessarily performance.




03
The Solution
Multi-Lamellar Emulsion (MLE) layered delivery architecture.

By mimicking the skin’s natural lipid structure, MLE technology allows coordinated absorption while reinforcing barrier integrity. Peptide complex, antioxidants and humectants are delivered within a unified system not as separate, competing layers.

Ingredient study
81.25%
Palmitoyl Tripeptide-1​
In a 14-day study of Palmitoyl Tripeptide-1, 81.25% of participants reported smoother looking skin.​
Read Full Study
Unique Base, Adaptive Face Cream

Unique Base, Adaptive Face Cream

The foundation of intelligent skin health.

A coordinated hydration and peptide system designed to replace multi-step routines while supporting barrier strength and visible firmness.

CHF 260.00 / 50ml

Magic Lift, Eye Cream


Magic Lift, Eye Cream


Precision support for the eye area.

Targeted care developed to complement Unique Base, addressing delicate skin with an immediate firming and lifting effect.

CHF 200.00 / 15ml

Begin Your Routine

One Cream.

Everything Your Skin Needs.

Swiss-developed. Clinician-formulated. Designed to simplify and to outperform.

Swiss Made & Certified Swiss Made & Certified
Complimentary Shipping Complimentary Shipping